Epigallocatechin Gallate Inhibits Biofilm Formation by Ocular Staphylococcal Isolates

作者：Anna Rita Blanco, Andrea Sudano-Roccaro, Giovanna Carmela Spoto, Antonia Nostro, Dario Rusciano · 发表于：Antimicrobial Agents and Chemotherapy · 年份：2005 · DOI：10.1128/aac.49.10.4339-4343.2005 · 被引用次数：135 · 研究领域：Bacterial biofilms and quorum sensing、Ocular Infections and Treatments、Oral microbiology and periodontitis research

Epigallocatechin gallate (EGCg), the main polyphenol component of green tea, has several antibacterial properties. Here we show that sub-MICs of EGCg appear to decrease slime production, therefore inhibiting biofilm formation by ocular staphylococcal isolates previously characterized for the presence of ica genes by the Congo red agar plate assay and for adhesion to microtiter plates.