A Two‐Channel Ratiometric Electrochemical Biosensor for In Vivo Monitoring of Copper Ions in a Rat Brain Using Gold Truncated Octahedral Microcages

作者：Xiaolan Chai, Xinguang Zhou, Anwei Zhu, Limin Zhang, Yao Qin, Guoyue Shi, Yang Tian · 发表于：Angewandte Chemie International Edition · 年份：2013 · DOI：10.1002/anie.201302958 · 被引用次数：142 · 研究领域：Electrochemical Analysis and Applications、Advanced biosensing and bioanalysis techniques、Electrochemical sensors and biosensors

Brain chemistry: A biosensor has been developed for in vivo determination of copper ions in a rat brain by using gold truncated octahedral microcages. The significant analytical performance of the present biosensor, as well as the properties of a carbon fiber microelectrode have provided a direct and reliable approach for monitoring cerebral metal ions (W.E.=working electrode; see picture).