Staging of gastrulating mouse embryos by morphological landmarks in the dissecting microscope

作者：Karen M. Downs, Timothy J Davies · 发表于：Development · 年份：1993 · DOI：10.1242/dev.118.4.1255 · 被引用次数：594 · 研究领域：Animal Genetics and Reproduction、Pluripotent Stem Cells Research、Molecular Biology Techniques and Applications

We describe and illustrate a set of morphological landmarks for classifying mouse embryos by gross morphology from before gastrulation to the beginning of organogenesis. These landmarks are visible at the resolution of the dissecting microscope in embryos that are intact except for reflexion of Reichert's membrane. Adoption of these criteria should facilitate interpretation of both the expression patterns of genes and the consequences of experimental manipulation of embryos during early postimplantation development.