CLASS II ANTIGENS AND DISEASE SUSCEPTIBILITY

作者：Gerald T. Nepom · 发表于：Annual Review of Medicine · 年份：1995 · DOI：10.1146/annurev.med.46.1.17 · 被引用次数：61 · 研究领域：Diabetes and associated disorders、T-cell and B-cell Immunology、Systemic Lupus Erythematosus Research

The role for HLA typing in autoimmune disease is changing with the recognition that HLA markers can identify patients with poor prognosis in some autoimmune disease. Aggressive therapeutic intervention in patients with such HLA prognostic markers has the potential to improve or prevent progressive disease outcomes in a select group of patients.