A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor–negative breast cancer in the general population

作者：EMBRACE, Antonis C. Antoniou, GEMO Study Collaborators, HEBON, kConFab, SWE-BRCA, MOD SQUAD, GENICA, Xianshu Wang, Zachary S. Fredericksen, Lesley McGuffog, Robert F. Tarrell, Olga M. Sinilnikova, Sue C. Healey, Jonathan James Morrison, Christiana Kartsonaki, Timothy G. Lesnick, Maya Ghoussaini, Daniel Barrowdale, Susan Peock, Margaret Cook, Clare Oliver, Debra Frost, Diana Eccles, D. Gareth Evans, Rosalind A. Eeles, Louise Izatt, Carol Chu, Fiona Douglas, Joan Paterson, Dominique Stoppa-Lyonnet, Claude Houdayer, Sylvie Mazoyer, Sophie Giraud, Christine Lasset, Audrey Remenieras, Olivier Caron, Agnès Hardouin, Pascaline Berthet, Frans B.L. Hogervorst, Matti A. Rookus, Agnes Jager, Ans van den Ouweland, Nicoline Hoogerbrugge, Rob B. van der Luijt, Hanne E.J. Meijers-Heijboer, E. Gómez, Peter Devilee, Maaike P.G. Vreeswijk, Jan Lubiński, Anna Jakubowska, Jacek Gronwald, Tomasz Huzarski, Tomasz Byrski, Bohdan Górski, Cezary Cybulski, Amanda B. Spurdle, Helene Holland, David E Goldgar, Esther M. John, John L. Hopper, Melissa C. Southey, Saundra S. Buys, Mary Beryl Daly, Mary Beth Terry, Rita Katharina Schmutzler, Barbara Wappenschmidt, Christoph Engel, Alfons Meindl, Sabine Preisler‐Adams, Norbert Arnold, Dieter Niederacher, Christian Sutter, Susan M. Domchek, Katherine L. Nathanson, Timothy R. Rebbeck, Joanne L. Blum, MARION R. PIEDMONTE, Gustavo C. Rodriguez, Katie Wakeley, John F. Boggess, Jack Basil, Stephanie V. Blank, Eitan Friedman, Bella Kaufman, Yael Laitman, Roni Milgrom, Irene Louise Andrulis, Gord Glendon, Hilmi Özçelik, Tomas Kirchhoff, Joseph Vijai, Mia M. Gaudet, David Altshuler, Candace Guiducci, Niklas Loman, Katja Harbst, Johanna Rantala, Hans Ehrencrona, Anne‐Marie Gerdes, Mads Thomassen, Lone Sunde, Paolo Peterlongo, Siranoush Manoukian, Bernardo Bonanni, Alessandra Viel, Paolo Radice, Trinidad Caldés, Miguel de la Hoya, Christian Fridolin Singer, Anneliese Fink-Retter, Mark H. Greene, Phuong L Mai, Jennifer T. Loud, Lucia Guidugli, Noralane M. Lindor, Thomas van Overeem Hansen, Finn C. Nielsen, Ignacio Blanco, Conxi Lázaro, Judy Garber, Susan J. Ramus, Simon A. Gayther, Catherine Phelan, Stephen Narod, Csilla I. Szabo, Javier Benítez, Ana Osório, Heli A. Nevanlinna, Tuomas Heikkinen, Maria Adelaide Caligo, Mary Stanley Beattie, Ute Hamann, Andrew K Godwin, Marco Montagna, Cinzia Casella, Susan L. Neuhausen, Beth Y Karlan, Nadine Tung, Amanda Ewart Toland, Jeffrey N. Weitzel, Olofunmilayo I. Olopade, Jacques Simard, Penny Soucy, Wendy S. Rubinstein, Aðalgeir Arason, Gad Rennert, Nicholas G. Martin, Grant W. Montgomery, Jenny C. Chang-Claude, Dieter Flesch-Janys, Hiltrud B. Brauch, Gianluca Severi, Laura Baglietto, Angela Cox, Simon S. Cross, Penelope L. Miron, Sue Gerty, William Tapper, Drakoulis Yannoukakos, George Fountzilas, Peter A Fasching, Matthias W Beckmann, Isabel dos‐Santos‐Silva, Julian Peto, Diether Lambrechts, Robert Paridaens, Thomas Rüdiger, Asta Försti, Robert Winqvist, Katri Pylkäs, Robert B. Diasio, Adam M. Lee, Jeanette E. Eckel‐Passow, Celine M. Vachon, Fiona M. Blows, Kristy E. Driver, Alison M. Dunning, Paul D.P. Pharoah, Kenneth Offit, V. Shane Pankratz, Hakon Hakonarson, Georgia Chenevix‐Trench, Douglas F. Easton, Fergus J. Couch · 发表于：Nature Genetics · 年份：2010 · DOI：10.1038/ng.669 · 被引用次数：344 · 研究领域：BRCA gene mutations in cancer、Genomic variations and chromosomal abnormalities、Genetic Associations and Epidemiology