TM or not TM: transmembrane protein prediction with low false positive rate using DAS-TMfilter

作者：Miklós Cserző, Frank Eisenhaber, Birgit Eisenhaber, István Simon · 发表于：Bioinformatics · 年份：2003 · DOI：10.1093/bioinformatics/btg394 · 被引用次数：101 · 研究领域：Machine Learning in Bioinformatics、Advanced Proteomics Techniques and Applications、Bioinformatics and Genomic Networks

UNLABELLED: Web-based servers implementing the DAS-TMfilter algorithm have been launched at three mirror sites and their usage is described. The underlying computer program is an upgraded and modified version of the DAS-prediction method. The new server is (approximately 1 among 100 unrelated queries) while the high efficiency of the original algorithm locating TM segments in queries is preserved (sensitivity of approximately 95% among documented proteins with helical TM regions). AVAILABILITY: The server operates at three mirror sites: http://mendel.imp.univie.ac.at/sat/DAS/DAS.html, http://wooster.bip.bham.ac.uk/DAS.html and http://www.enzim.hu/DAS/DAS.html. The program is available on request.