The role of periodontitis in cardiovascular disease

作者：Kåre Buhlin · 发表于：Figshare · 年份：2004 · 被引用次数：1 · 研究领域：Oral microbiology and periodontitis research

Periodontitis and cardiovascular disease (CVD) are both common diseases affecting a large part of the society. Both diseases are considered to have a chronic inflammatory origin. During the last decades research has focused on a possible link between them. Most of these studies have examined the epidemiological relationship between periodontal disease and CVD. The biological reason for a link has been discussed, but is unclear. In this thesis an association between periodontal disease and CVD the diseases in an adult Swedish population have been studied, and several biological risk factors related to atherosclerosis in periodontitis patients investigated. The first aim of these studies was to investigate if there was a connection between the inflammatory diseases, atherosclerosis and periodontitis, in an adult Swedish population (paper I, III), and if this connection also was found in a female population (paper IV). Secondly we wanted to investigate the mechanism behind it, if a connection was established (paper V). The third aim of these investigations was to investigate if self-reported questionnaires of oral health were reliable in health surveys (paper II). The fourth and final purpose of this thesis was to investigate the oral health status in Swedish population and peoples attitudes towards oral and dental health (paper III). Paper I and paper III showed that there was a relationship between self-reported CVD and bleeding gums, and other oral health parameters in an adu...