Functional and Evolutionary Insights from the Genomes of Three Parasitoid Nasonia Species

作者：John H. Werren, Stephen Richards, Christopher A. Desjardins, Oliver Niehuis, Jürgen Gadau, John K. Colbourne, The Nasonia Genome Working Group, Leo W. Beukeboom, Claude Desplan, Christine G. Elsik, Cornelis J.P. Grimmelikhuijzen, Paul Kitts, Jeremy Lynch, Terence D. Murphy, Deodoro C. S. G. Oliveira, Christopher D. Smith, Louis van de Zande, Kim C. Worley, Evgeny M. Zdobnov, Maarten Aerts, Štefan Albert, Víctor Hugo Anaya-Muñoz, Juan Manuel Anzola, Angel Roberto Barchuk, Susanta K. Behura, Agata N. Bera, May R. Berenbaum, Rinaldo C. Bertossa, Márcia Maria Gentile Bitondi, Seth R. Bordenstein, Peer Bork, Erich Bornberg‐Bauer, Marleen Brunain, Giuseppe Cazzamali, Lesley Chaboub, Joseph Chacko, Dean Chavez, Christopher Childers, Jeong-Hyeon Choi, Michael E. Clark, Charles Claudianos, Rochelle A. Clinton, Andrew Cree, Alexandre S. Cristino, Phat Dang, Alistair C. Darby, Dirk C. de Graaf, Bart Devreese, Huyen Dinh, Rachel Edwards, Navin Elango, Eran Elhaik, Olga Ermolaeva, Jay D. Evans, Sylvain Forêt, Gerald Fowler, Daniel Gerlach, Joshua D. Gibson, Donald Gilbert, Dan Graur, Stefan Gründer, Darren E. Hagen, Yi Han, Frank Hauser, Dan Hultmark, Henry C. Hunter, Gregory D. D. Hurst, Shalini N. Jhangian, Huaiyang Jiang, Reed M. Johnson, Andrew K. Jones, Thomas Junier, Tatsuhiko Kadowaki, Albert Kamping, Yuri Kapustin, Bobak Kechavarzi, Jaebum Kim, Jay Kim, Boris Kiryutin, Tosca Koevoets, Christie Kovar, Evgenia V. Kriventseva, Robert Kucharski, Heewook Lee, Sandra L. Lee, Kristin Lees, Lora Lewis, David W. Loehlin, John M. Logsdon, Jacqueline Lopez, Ryan J. Lozado, Donna Maglott, Ryszard Maleszka, Anoop Mayampurath, Danielle J. Mazur, Marcella A. McClure, Andrew D. Moore, Margaret Morgan, Jean Muller, Mónica Muñoz-Torres, Donna M. Muzny, Lynne V. Nazareth, Susanne Neupert, Ngoc B. Nguyen, Francis Morais Franco Nunes, John G. Oakeshott, Geoffrey Okwuonu, Bart A. Pannebakker, Vikas Pejaver, Zuogang Peng, Stephen C. Pratt, Reinhard Predel, Ling Pu, Hilary Ranson, Rhitoban Raychoudhury, Andreas Rechtsteiner, Jeffrey G. Reid, Megan Riddle, Jeanne Romero‐Severson, Miriam Rosenberg, Timothy B. Sackton, David B. Sattelle, Helge Schlüns, Thomas Schmitt, Martina Schneider, Andreas Schüler, Andrew Schurko, David M. Shuker, Zilá Luz Paulino Simões, Saurabh Sinha, Zachary D. Smith, Alexandre Souvorov, Andreas Springauf, Elisabeth Stafflinger, Deborah E. Stage, Mario Stanke, Yoshiaki Tanaka, Arndt Telschow, Carol Trent, Selina Vattathil, Lumi Viljakainen, Kevin W. Wanner, Robert M. Waterhouse, James B. Whitfield, Timothy E. Wilkes, Michael R. Williamson, Judith H. Willis, Florian Wolschin, Stefan Wyder, Takuji Yamada, Soojin V. Yi, Courtney N. Zecher, Lan Zhang, Richard A. Gibbs · 发表于：Science · 年份：2010 · DOI：10.1126/science.1178028 · 被引用次数：908 · 研究领域：Insect symbiosis and bacterial influences、Insect-Plant Interactions and Control、Insect and Arachnid Ecology and Behavior

We report here genome sequences and comparative analyses of three closely related parasitoid wasps: Nasonia vitripennis, N. giraulti, and N. longicornis. Parasitoids are important regulators of arthropod populations, including major agricultural pests and disease vectors, and Nasonia is an emerging genetic model, particularly for evolutionary and developmental genetics. Key findings include the identification of a functional DNA methylation tool kit; hymenopteran-specific genes including diverse venoms; lateral gene transfers among Pox viruses, Wolbachia, and Nasonia; and the rapid evolution of genes involved in nuclear-mitochondrial interactions that are implicated in speciation. Newly developed genome resources advance Nasonia for genetic research, accelerate mapping and cloning of quantitative trait loci, and will ultimately provide tools and knowledge for further increasing the utility of parasitoids as pest insect-control agents.