N-((1 S)-1-{[4-((2 S)-2-{[(2,4-Dichlorophenyl)sulfonyl]amino}-3-hydroxypropanoyl)-1-piperazinyl]carbonyl}-3-methylbutyl)-1-benzothiophene-2-carboxamide (GSK1016790A), a Novel and Potent Transient Receptor Potential Vanilloid 4 Channel Agonist Induces Urinary Bladder Contraction and Hyperactivity: Part I

作者：Kevin S. Thorneloe, Anthony C. Sulpizio, Zuojun Lin, David J. Figueroa, Angela K. Clouse, Gerald P. McCafferty, Tim P. Chendrimada, Erin S. R. Lashinger, Earl Gordon, Louise Christine Evans, Blake A. Misajet, Douglas James DeMarini, Josephine H.L. Nation, Linda Casillas, Robert W. Marquis, Bartholomew J. Votta, Steven A. Sheardown, Xiaoping Xu, David P. Brooks, Nicholas J. Laping, Timothy D. Westfall · 发表于：Journal of Pharmacology and Experimental Therapeutics · 年份：2008 · DOI：10.1124/jpet.108.139295 · 被引用次数：408 · 研究领域：Ion Channels and Receptors、Circadian rhythm and melatonin、Urinary Bladder and Prostate Research