One Approach to Cyclic Carbonates via a Three-Component Cyclization of Phenacyl Bromide, CO 2 , and Aldehyde

作者：Peng Yan, Xueqin Tan, Huanwang Jing, Shuhui Duan, Xiaoxuan Wang, Zhong‐Li Liu · 发表于：The Journal of Organic Chemistry · 年份：2011 · DOI：10.1021/jo1020294 · 被引用次数：20 · 研究领域：Carbon dioxide utilization in catalysis、Asymmetric Hydrogenation and Catalysis、Chemical Synthesis and Reactions

A three-component cyclization reaction was designed for synthesizing cyclic carbonates in a single operation from phenacyl bromide, CO(2), and aldehyde in the presence of lithium diisopropylamide (LDA). These novel reactions were achieved under extremely mild conditions to generate the target products in moderate to good yields within 10 min.