The reletion between nutrition and exhibition of the gene antennales ( Drosophila melanogaster )

作者：Cecil Gordon, James H. Sang · 发表于：Proceedings of the Royal Society B Biological Sciences · 年份：1941 · DOI：10.1098/rspb.1941.0010 · 被引用次数：35 · 研究领域：Insect Resistance and Genetics、Viral Infectious Diseases and Gene Expression in Insects、Insect and Arachnid Ecology and Behavior

Abstract The gene Antennaless located on the second chromosome of Drosophilamelanogaster prevents formation of antennae under appropriate conditions of culture. In normal cultures phenotypic indices (§1) of pure lines are at first high, then decline to a minimum about the fourth day, and subsequently rise to near the initial level. This emergence effect is not due to selective mortality of genotypes dis­tinguished by modifiers of Antennaless. It is due to external changes in normal culture media. As indicated by the temperature-effective period of the normal fully fed larva, the time of action of the gene is between the third and fourth days of larval life. Within a small range examined (5°C), temperature changes have a striking effect on exhibition, when the medium is sterile. On normal media, changing behaviour of yeast populations masks this effect. An apparent association between changing pH of a normal medium and changing frequency of exhibition in a normal culture is brought about by a complex series of interacting agencies. It is possible to correlate successive changes of exhibition frequency in a normal culture with: (a) gross changes due to the activities of the larvae; (b) biochemical changes in the yeast diet arising from differential fertility or mortality of yeast strains and from the direct action of changing conditions upon the metabolism of the microflora. Yeasts produce X substances which, encourage, and Y substances which inhibit, exhibition of the gene Ant...