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Polypyrimidine Tract Binding Protein Antagonizes Exon Definition

作者:Eric J. Wagner, Mariano A. García-Blanco · 发表于:Molecular and Cellular Biology · 年份:2001 · DOI:10.1128/mcb.21.10.3281-3288.2001 · 被引用次数:380 · 研究领域:Genomics and Chromatin Dynamics、RNA and protein synthesis mechanisms、RNA modifications and cancer

The removal of introns from mRNA precursors (pre-mRNAs) involves two relatively straightforward chemical reactions. The recognition of intron-exon boundaries, the splice sites, however, requires th...