Enzyme-Linked Immunosorbent Assay for Quantitation of Human Antibodies to Pneumococcal Polysaccharides

作者：Catherine M. Wernette, Carl E. Frasch, Dace Viceps Madore, George M. Carlone, David Goldblatt, Brian D. Plikaytis, William H. Benjamin, Sally A. Quataert, Steve Hildreth, Daniel J. Sikkema, Helena M. Käyhty, Ingileif Jónsdóttir, Moon H. Nahm · 发表于：Clinical and Vaccine Immunology · 年份：2003 · DOI：10.1128/cdli.10.4.514-519.2003 · 被引用次数：339 · 研究领域：Pneumonia and Respiratory Infections、Streptococcal Infections and Treatments、Respiratory viral infections research

Streptococcus pneumoniae is a major human pathogen causing pneumonia, sepsis, meningitis, and otitis media ([12][1]). It causes infections most often in young children ([12][1]) and elderly adults ([1][2]) because their immune systems are either unprepared or unable to respond effectively to