Antiulcerogenic Activity of Alhagi maurorum .

作者：A.S. Awaad Amani, Derek J. Maitland, Gamal A. Soliman · 发表于：Pharmaceutical Biology · 年份：2006 · DOI：10.1080/13880200600714160 · 被引用次数：77 · 研究领域：Natural Antidiabetic Agents Studies、Natural product bioactivities and synthesis、Phytochemistry and Bioactive Compounds

Six main flavonoid glycosides were isolated, for the first time, from the ethanol extract of Alhagi maurorum Boiss (Leguminosae).. They were identified as kaempferol, chrysoeriol, isorhamnetin, chrysoeriol-7-O.-xylosoid, kaempferol-3-galactorhamnoside, and isorhamnetin 3-O.-β-D-apio-furanosyl (1-2) β-D-galactopyranoside. Their identities were established by m.p., UV, EI-mass, Fab-mass, 600 MHz 1H and 13C NMR. The total extract (300 and 400 mg/kg) and two of the isolated compounds (chrysoeriol 7-O.-xylosoid and kaempferol-3-galactorhamnoside, 100 mg/kg each) showed a very promising antiulcerogenic activity with curative ratios 66.31%, 69.57%, 75.49%, and 77.93%, respectively.