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Exercise and Nutrition to Target Protein Synthesis Impairments in Aging Skeletal Muscle

作者:Jared M. Dickinson, Elena Volpi, Blake B. Rasmussen · 发表于:Exercise and Sport Sciences Reviews · 年份:2013 · DOI:10.1097/jes.0b013e3182a4e699 · 被引用次数:139 · 研究领域:Muscle metabolism and nutrition、Sports Performance and Training、Muscle Physiology and Disorders

In Brief The loss of skeletal muscle size and function with aging and sarcopenia may be related, in part, to an age-related muscle protein synthesis impairment. In this review, we discuss to what extent aging affects skeletal muscle protein synthesis and how nutrition and exercise can be used strategically to overcome age-related protein synthesis impairments and slow the progression of sarcopenia. This review discusses how aging affects the protein synthesis response of skeletal muscle to nutrition and exercise.