Isolation and structure elucidation of novel hypotensive agents, niazinin A, niazinin B, niazimicin and niaziminin A + B from Moringa oleifera: the first naturally occurring thiocarbamates

作者：Shaheen Faizi, Bina S. Siddiqui, Rubeena Saleem, Salimuzzaman Siddiqui, Khalid Aftab, Anwar-ul-Hassan Gilani · 发表于：Journal of the Chemical Society Perkin Transactions 1 · 年份：1992 · DOI：10.1039/p19920003237 · 被引用次数：48 · 研究领域：Moringa oleifera research and applications、Essential Oils and Antimicrobial Activity、Phytochemistry and Bioactivity Studies

Novel hypotensive principles, niazinin A 1, niazinin B 2, niazimicin 4 and niaziminin A and B 6+7, have been obtained from the ethanolic extract of the fresh leaves of Moringa oleifera, employing a bioassay-guided isolation procedure. Their structures have been elucidated through spectroscopic (including 2D NMR techniques) and chemical methods. These compounds are mustard oil glycosides which are very rare in Nature and are also the first examples of naturally occurring thiocarbamates.