History of vaccination

作者：Stanley Alan Plotkin · 发表于：Proceedings of the National Academy of Sciences · 年份：2014 · DOI：10.1073/pnas.1400472111 · 被引用次数：637 · 研究领域：Influenza Virus Research Studies、SARS-CoV-2 and COVID-19 Research、Vaccine Coverage and Hesitancy

Vaccines have a history that started late in the 18th century. From the late 19th century, vaccines could be developed in the laboratory. However, in the 20th century, it became possible to develop vaccines based on immunologic markers. In the 21st century, molecular biology permits vaccine development that was not possible before.