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Evaluation for liver transplantation in adults: 2013 practice guideline by the American Association for the Study of Liver Diseases and the American Society of Transplantation

作者:Paul Martin, Andrea F. DiMartini, Sandy Feng, Robert S. Brown, Michael B. Fallon · 发表于:Hepatology · 年份:2013 · DOI:10.1002/hep.26972 · 被引用次数:1041 · 研究领域:Liver Disease Diagnosis and Treatment、Liver Disease and Transplantation、Hepatitis C virus research

This practice guideline has been approved by the American Association for the Study of Liver Diseases and the American Society of Transplantation and represents the position of both Associations. Guidelines on Evaluation for Liver Transplantation (LT) were published in 2005 by the American Association for the Study of Liver Diseases (AASLD).1 In the interim there have been major advances in the management of chronic liver disease, most notably in antiviral therapy for chronic viral hepatitis. Nonalcoholic fatty liver disease (NAFLD) has assumed increasing prominence as a cause of cirrhosis and hepatocellular carcinoma (HCC) requiring liver transplant.2 Furthermore, individual disease indications for LT such as HCC have been refined3 and specific guidelines have appeared for chronic viral hepatitis.4 Reflecting the need for a multidisciplinary approach to the evaluation of this complex group of patients who have the comorbidities typical of middle age, recommendations have been developed to assist in their cardiac management.5 With an increasing number of long-term survivors of LT there has been a greater focus on quality of life and attention to comorbid conditions impacting recipient longevity.6 The purpose of the current Guidelines is to provide an evidence-based set of recommendations for the evaluation of adult patients who are potentially candidates for LT. These recommendations provide a data-supported approach. They are based on the following: (1) formal review and ana...