First Identification of Pseudomonas aeruginosa Isolates Producing a KPC-Type Carbapenem-Hydrolyzing β-Lactamase

作者：María Virginia Villegas, Karen Lolans, Adriana Correa, Juan Nicolás Kattán, Jaime Alberto López, John Peter Quinn · 发表于：Antimicrobial Agents and Chemotherapy · 年份：2007 · DOI：10.1128/aac.01405-06 · 被引用次数：295 · 研究领域：Antibiotic Resistance in Bacteria、Pharmaceutical and Antibiotic Environmental Impacts、Bacterial biofilms and quorum sensing

In Medellin, Colombia, three Pseudomonas aeruginosa isolates with high-level carbapenem resistance (MIC>or=256 microg/ml) and an isolate of Citrobacter freundii with reduced susceptibility to imipenem produced the plasmid-mediated class A carbapenemase KPC-2. This is the first report of a KPC-type beta-lactamase identified outside of the family Enterobacteriaceae.