Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma

作者：Ignacio Pujol Varela, Patrick S. Tarpey, Keiran M. Raine, Dachuan Huang, Choon Kiat Ong, Philip Stephens, Helen Ruth Davies, David Jones, Meng Lin, Jon W. Teague, Graham R. Bignell, Adam P. Butler, Juok Cho, Gillian L. Dalgliesh, Danushka Galappaththige, Chris Greenman, Claire W. Hardy, Mingming Jia, Calli Latimer, King Wai Lau, John Lindsay Marshall, Stuart McLaren, Andrew H. Menzies, Laura J. Mudie, Lucy A. Stebbings, David A. Largaespada, Lodewyk F.A. Wessels, Stephane Richard, Richard J. Kahnoski, JOHN G. ANEMA, David Arthur Tuveson, Pedro Antonio Pérez-Mancera, Ville Mustonen, Andrej Fischer, David J. Adams, Alistair G. Rust, Waraporn Chan-on, Chutima Subimerb, Karl J. Dykema, Kyle Furge, Peter J. Campbell, Bin Tean Teh, Michael R. Stratton, P. Andrew Futreal · 发表于：Nature · 年份：2011 · DOI：10.1038/nature09639 · 被引用次数：1297 · 研究领域：Chromatin Remodeling and Cancer、Renal and related cancers、Renal cell carcinoma treatment