Molecular Epidemiology of Methicillin-Resistant Staphylococcus aureus

作者：Bo Shopsin, Barry N. Kreiswirth · 发表于：Emerging infectious diseases · 年份：2001 · DOI：10.3201/eid0702.010236 · 被引用次数：153 · 研究领域：Antimicrobial Resistance in Staphylococcus、Bacterial Identification and Susceptibility Testing、Mycobacterium research and diagnosis

Subtyping methicillin- resistant Staphylococcus aureus (MRSA) isolates and tracking nosocomial infections have evolved from phenotypic to genotypic approaches; most laboratories now depend on pulsed-field gel electrophoresis (PFGE). We discuss the limitations of current image-based genotyping methods, including PFGE, and the advantages (including ease of entering data into a database) of using DNA sequence analysis to control MRSA infections in health-care facilities.