Simulation of the temperature increase in human cadaver retina during direct illumination by 150-kHz femtosecond laser pulses

作者：Hui Sun, Nóra Hosszúfalusi, Eric Mikula, Tibor Juhász · 发表于：Journal of Biomedical Optics · 年份：2011 · DOI：10.1117/1.3631788 · 被引用次数：17 · 研究领域：Intraocular Surgery and Lenses、Ocular and Laser Science Research、Corneal surgery and disorders

We have developed a two-dimensional computer model to predict the temperature increase of the retina during femtosecond corneal laser flap cutting. Simulating a typical clinical setting for 150-kHz iFS advanced femtosecond laser (0.8- to 1-μJ laser pulse energy and 15-s procedure time at a laser wavelength of 1053 nm), the temperature increase is 0.2°C. Calculated temperature profiles show good agreement with data obtained from ex vivo experiments using human cadaver retina. Simulation results obtained for different commercial femtosecond lasers indicate that during the laser in situ keratomileusis procedure the temperature increase of the retina is insufficient to induce damage.