Blood Banking in Living Droplets

作者：Josh Samot, Sangjun Moon, Lei Shao, Xiaohui Zhang, Feng Xu, Youngseok Song, Hasan Onur Keleş, Laura Y. Matloff, Jordan Markel, Utkan Demirci · 发表于：PLoS ONE · 年份：2011 · DOI：10.1371/journal.pone.0017530 · 被引用次数：38 · 研究领域：Blood donation and transfusion practices、Blood transfusion and management

Blood banking has a broad public health impact influencing millions of lives daily. It could potentially benefit from emerging biopreservation technologies. However, although vitrification has shown advantages over traditional cryopreservation techniques, it has not been incorporated into transfusion medicine mainly due to throughput challenges. Here, we present a scalable method that can vitrify red blood cells in microdroplets. This approach enables the vitrification of large volumes of blood in a short amount of time, and makes it a viable and scalable biotechnology tool for blood cryopreservation.