The Unstable Atheroma

作者：Richard Theodore Lee, Peter Libby · 发表于：Arteriosclerosis Thrombosis and Vascular Biology · 年份：1997 · DOI：10.1161/01.atv.17.10.1859 · 被引用次数：562 · 研究领域：Atherosclerosis and Cardiovascular Diseases、Coronary Interventions and Diagnostics、Protease and Inhibitor Mechanisms

Factors increasing stress Factors weakening the cap • thin fibrous cap • I collagen synthesis • large lipid pool • T collagen degradation • less stenotic lesions • T macrophages, T-cells • T (ester/free) cholesterol • 4-smooth muscle cells Key Words • unstable lesions • fibrous cap • plaque rupture