Deficiency or inhibition of oxygen sensor Phd1 induces hypoxia tolerance by reprogramming basal metabolism

作者：Julián Aragonés, Martin A. Schneider, Katie Van Geyte, Peter Fraisl, Tom Dresselaers, Massimiliano Mazzone, Ruud Dirkx, Serena Zacchigna, Hélène Lemieux, Nam Ho Jeoung, Diether Lambrechts, Tammie Bishop, Peggy Lafuste, Antonio Díez‐Juan, Sarah K. Harten, Pieter Van Noten, Katrien De Bock, Carsten Willam, Marc Tjwa, Alexandra Grosfeld, Rachel Navet, Lieve Moons, Thierry VandenDriessche, Christophe M. Deroose, Bhathiya Wijeyekoon, Johan L. Nuyts, Bénédicte F. Jordan, Robert Silasi‐Mansat, Florea Lupu, Mieke A. Dewerchin, Christopher William Pugh, Phil Salmon, Luc Mortelmans, Bernard Gallez, Frans Gorus, Johan G. Buyse, Francis E. Sluse, Robert Adron Harris, Erich Gnaiger, Peter Hespel, Paul Van Hecke, Frans C Schuit, Paul Van Veldhoven, Peter John Ratcliffe, Myriam I Baes, Patrick Henry Maxwell, Peter Carmeliet · 发表于：Nature Genetics · 年份：2008 · DOI：10.1038/ng.2007.62 · 被引用次数：477 · 研究领域：Cancer, Hypoxia, and Metabolism、High Altitude and Hypoxia、Mitochondrial Function and Pathology