ANTIGENIC RELATIONSHIPS BETWEEN GROUPS B AND G STREPTOCOCCI

作者：Stephen N. Curtis, Richard M. Krause · 发表于：The Journal of Experimental Medicine · 年份：1964 · DOI：10.1084/jem.120.4.629 · 被引用次数：72 · 研究领域：Neonatal and Maternal Infections、Pneumonia and Respiratory Infections、Streptococcal Infections and Treatments

Trypsinized cell walls of Group B hemolytic streptococci are composed of a group-specific carbohydrate and mucopeptide. The carbohydrate extracted with hot formamide is composed of rhamnose, N-acetylglucosamine, and galactose. Quantitative precipitin inhibition studies have shown that L rhamose is the significant component of the antigenic determinant. The cross-reactivity between B and G carbohydrates is dependent upon the fact that Lrhamose is a determinant sugar in both antigens.