Inhibition of Aggregation of the Slime Mould Dictyostelium Discoideum by a Factor Diffusing from Escherichia Coli

作者：Blake Shaffer · 发表于：Journal of Cell Science · 年份：1966 · DOI：10.1242/jcs.1.4.391 · 被引用次数：7 · 研究领域：Cellular Mechanics and Interactions、Slime Mold and Myxomycetes Research、Biocrusts and Microbial Ecology

A factor diffuses from Escherichia coli that temporarily or permanently prevents separate pre-aggregation cells of Dictyostelium discoideum from forming aggregation centres or streams. Centres are inhibited at a greater distance from the bacteria than are streams. The inhibitor does not support the slime-mould's growth, and it has different properties from previously discovered aggregation-centre inhibitors released by the amoebae themselves. The factor, as produced, does not inhibit Polysphondylium violaceum cells from forming centres or streams. Yet although E. coli itself attracts pre-aggregation P. violaceum cells, it does not mimic a P. violaceum aggregate in inducing them to form streams.