DnaSP, DNA polymorphism analyses by the coalescent and other methods

作者：Julio Rozas, Juan Carlos Sánchez-DelBarrio, Xavier Messeguer, R. Rozas · 发表于：Bioinformatics · 年份：2003 · DOI：10.1093/bioinformatics/btg359 · 被引用次数：6204 · 研究领域：Genetic diversity and population structure、Genetic Associations and Epidemiology、Evolution and Genetic Dynamics

SUMMARY: DnaSP is a software package for the analysis of DNA polymorphism data. Present version introduces several new modules and features which, among other options allow: (1) handling big data sets (approximately 5 Mb per sequence); (2) conducting a large number of coalescent-based tests by Monte Carlo computer simulations; (3) extensive analyses of the genetic differentiation and gene flow among populations; (4) analysing the evolutionary pattern of preferred and unpreferred codons; (5) generating graphical outputs for an easy visualization of results. AVAILABILITY: The software package, including complete documentation and examples, is freely available to academic users from: http://www.ub.es/dnasp