Airway Mucus Function and Dysfunction

作者：John V. Fahy, Burton F. Dickey · 发表于：New England Journal of Medicine · 年份：2010 · DOI：10.1056/nejmra0910061 · 被引用次数：1755 · 研究领域：Pediatric health and respiratory diseases、Respiratory and Cough-Related Research、Inhalation and Respiratory Drug Delivery

Pulmonary defense against environmental injury depends on airway mucus, which traps inhaled toxins that are then cleared from the lungs by ciliary beating and cough. This review examines the normal and abnormal formation and clearance of mucus, as well as the therapy of mucus dysfunction.