The BTB/POZ domain: a new protein-protein interaction motif common to DNA- and actin-binding proteins.

作者：Olivier Albagli, Philippe Dhordain, Clotilde Deweindt, Gérard Lecocq, Dominique Leprince · 发表于：PubMed · 年份：1995 · 被引用次数：386 · 研究领域：Cancer-related gene regulation、Ubiquitin and proteasome pathways、Genomics and Chromatin Dynamics

The BTB/POZ domain defines a newly characterized protein-protein interaction interface. It is highly conserved throughout metazoan evolution and generally found at the NH2 terminus of either actin-binding or, more commonly, nuclear DNA-binding proteins. By mediating protein binding in large aggregates, the BTB/POZ domain serves to organize higher order macromolecular complexes involved in ring canal formation or chromatin folding.