Prevalence of Enteric Pathogens among International Travelers with Diarrhea Acquired in Kenya (Mombasa), India (Goa), or Jamaica (Montego Bay)

作者：Zhi‐Dong Jiang, Brett S Lowe, M P Verenkar, David Ashley, Robert J. Steffen, Nadia Tornieporth, Frank von Sonnenburg, Peter G. Waiyaki, Herbert L. DuPont · 发表于：The Journal of Infectious Diseases · 年份：2002 · DOI：10.1086/338834 · 被引用次数：268 · 研究领域：Travel-related health issues、Hepatitis Viruses Studies and Epidemiology、Viral gastroenteritis research and epidemiology

Stools from tourists from Europe and North America who acquired diarrhea in Mombasa (Kenya), Goa (India), or Montego Bay (Jamaica) were examined for enteric pathogens. Enterotoxigenic Escherichia coli (ETEC) was the most common pathogen (25%) identified in the 3 locations. Isolation of Shigella species was more frequent in Goa and Mombasa than in Montego Bay (10%, 9%, and 0.3%, respectively; P <.005). Viruses (rotaviruses and enteric adenoviruses) were found in 9% of travelers to the 3 areas. Of 275 ETEC isolates in this study, 158 (57%) produced a defined colonization factor antigen (CFA). Coli surface 6 (CS6) was the most frequent and was found in 41%-52% of CFA/CS-positive ETEC isolates. The frequency of resistance among bacterial enteropathogens to traditional antimicrobial agents was particularly high throughout the study period in all 3 regions. Quinolones were active against the bacterial enteropathogens in the 3 sites.