Association of Television Viewing With Fasting and 2-h Postchallenge Plasma Glucose Levels in Adults Without Diagnosed Diabetes

作者：David Wayne Dunstan, Jo Salmon, Genevieve Nissa Healy, Jonathan Edward Shaw, Damien Jolley, Paul Zimmet, Neville G. Owen · 发表于：Diabetes Care · 年份：2007 · DOI：10.2337/dc06-1996 · 被引用次数：262 · 研究领域：Physical Activity and Health、Obesity, Physical Activity, Diet、Diabetes, Cardiovascular Risks, and Lipoproteins

OBJECTIVE: We examined the associations of television viewing time with fasting plasma glucose (FPG) and 2-h postchallenge plasma glucose (2-h PG) levels in Australian adults. RESEARCH DESIGN AND METHODS: A total of 8,357 adults aged > 35 years who were free from diagnosed diabetes and who attended a population-based cross-sectional study (Australian Diabetes, Obesity and Lifestyle Study [AusDiab]) were evaluated. Measures of FPG and 2-h PG were obtained from an oral glucose tolerance test. Self-reported television viewing time (in the previous week) was assessed using an interviewer-administered questionnaire. Homeostasis model assessment (HOMA) of insulin sensitivity (HOMA-%S) and beta-cell function (HOMA-%B) were calculated based on fasting glucose and insulin concentrations. RESULTS: After adjustment for confounders and physical activity time, time spent watching television in women was positively associated with 2-h PG, log fasting insulin, and log HOMA-%B and inversely associated with log HOMA-%S (P < 0.05) but not with FPG. No significant associations were observed with glycemic measures in men. The beta-coefficients across categories of average hours spent watching television per day (< 1.0, 1.0-1.9, 2.0-2.9, 3.0-3.9, and > or = 4.0) for 2-h PG in women were 0 (reference), 0.009, 0.047, 0.473, and 0.501, respectively (P for trend = 0.02). CONCLUSIONS: Our findings highlight the unique deleterious relationship of sedentary behavior (indicated by television viewing time...