The HMMTOP transmembrane topology prediction server

作者：Gábor Tusnády, István Simon · 发表于：Bioinformatics · 年份：2001 · DOI：10.1093/bioinformatics/17.9.849 · 被引用次数：1953 · 研究领域：Drug Transport and Resistance Mechanisms、RNA and protein synthesis mechanisms、Lipid Membrane Structure and Behavior

UNLABELLED: The HMMTOP transmembrane topology prediction server predicts both the localization of helical transmembrane segments and the topology of transmembrane proteins. Recently, several improvements have been introduced to the original method. Now, the user is allowed to submit additional information about segment localization to enhance the prediction power. This option improves the prediction accuracy as well as helps the interpretation of experimental results, i.e. in epitope insertion experiments. AVAILABILITY: HMMTOP 2.0 is freely available to non-commercial users at http://www.enzim.hu/hmmtop. Source code is also available upon request to academic users.