Identification of a Highly Divergent HIV Type 2 and Proposal for a Change in HIV Type 2 Classification

作者：Florence Damond, Michael Worobey, Pauline Campa, Isabelle Farfara, Gilles Colin, Sophie Matheron, Françoise Brun‐Vézinet, David L. Robertson, François Simon · 发表于：AIDS Research and Human Retroviruses · 年份：2004 · DOI：10.1089/0889222041217392 · 被引用次数：183 · 研究领域：HIV Research and Treatment、HIV/AIDS drug development and treatment、Herpesvirus Infections and Treatments

We report the complete genome sequence of a highly divergent strain of human immunodeficiency virus type 2 (HIV-2), 96FR12034, identified in France from a patient of West African origin. This lineage, H, represents only the third definitive instance of a monkey-to-human transfer of SIVsm that has given rise to pathogenic HIV-2. As the different "subtypes" of HIV-2 are analogous to the different groups of HIV-1 we propose that HIV-2 subtypes henceforth by renamed groups in agreement with the HIV Nomenclature Committee. The single-strain lineages C to G and the 96FR12034 lineage identified here should be considered only as putative groups until related strains are identified that confirm circulation of these viruses in the human population.