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The Charcot Foot in Diabetes

作者:Lee C. Rogers, Robert G. Frykberg, David G. Armstrong, Andrew J.M. Boulton, Michael Edmonds, Georges Ha Van, Agnès Hartemann, Frances L. Game, William Jeffcoate, Alexandra Jirkovská, Edward B. Jude, Stephan Morbach, William B. Morrison, Michael S. Pinzur, Dario Pitocco, Lee Sanders, Dane K. Wukich, Luigi Uccioli · 发表于:Diabetes Care · 年份:2011 · DOI:10.2337/dc11-0844 · 被引用次数:568 · 研究领域:Diabetic Foot Ulcer Assessment and Management、Bone and Joint Diseases、Skin Diseases and Diabetes

The diabetic Charcot foot syndrome is a serious and potentially limb-threatening lower-extremity complication of diabetes. First described in 1883, this enigmatic condition continues to challenge even the most experienced practitioners. Now considered an inflammatory syndrome, the diabetic Charcot foot is characterized by varying degrees of bone and joint disorganization secondary to underlying neuropathy, trauma, and perturbations of bone metabolism. An international task force of experts was convened by the American Diabetes Association and the American Podiatric Medical Association in January 2011 to summarize available evidence on the pathophysiology, natural history, presentations, and treatment recommendations for this entity.