A germline variant in the TP53 polyadenylation signal confers cancer susceptibility

作者：Swedish Low-risk Colorectal Cancer Study Group, Simon Stacey, Patrick Sulem, Áslaug Jónasdóttir, Gísli Másson, Jūlı́us Guðmundsson, Daniel Fannar Gudbjartsson, Ólafur Þ. Magnússon, Sigurjon Axel Gudjonsson, Bárður Sigurgeirsson, Kristin Thorisdottir, Rafn Ragnarsson, Kristrún R. Benediktsdóttir, Bjørn Andersen Nexø, Anne Marie Tjønneland, Kim Overvad, Péter Rudnai, Eugen Stelian Gurzau, Kvetoslava Koppová, Kari Hemminki, Cristina Corredera, Victoria Fuentelsaz, Pilar Grasa, Sebastián Bonilla Navarrete, Fernando Fuertes, María Dolores García-Prats, Enrique Sanambrosio, Angeles Panadero, Ana De Juan, Almudena García, Fernando Rivera, Dolores Planelles, Vincent Soriano, Celia Requena, Katja K.H. Aben, Michelle M. van Rossum, R.G.H.M. Cremers, Inge M. van Oort, Dick-Johan van Spronsen, Jack A. Schalken, Wilbert H.M. Peters, Brian T. Helfand, Jenny Donovan, Freddie Charles Hamdy, Daniel Liviu Badescu, O. Codreanu, Mariana Jinga, Irma Eva Csiki, Vali Constantinescu, Paula Badea, Ioan Nicolae Mateș, Daniela Dinu, Adrian Constantin, Dana Mateș, Sjöfn Kristjánsdóttir, Bjarni Agnar Agnarsson, Eiríkur Jónsson, Rosa Bjork Barkardottir, Guðmundur Einarsson, Fridbjörn Sigurdsson, Páll Helgi Möller, Tryggvi Stefánsson, Trausti Valdimarsson, Oskar T. Johannsson, Helgi Kjartan Sigurdsson, Þorvaldur Jónsson, Jon Gunnlaugur Jonasson, Laufey Tryggvadóttír, Terri Rice, Helen M. Hansen, Yuanyuan Xiao, Daniel Honore Lachance, Brian Patrick O’Neill, Matthew Kosel, Paul A. Decker, Guðmar Þorleifsson, Hrefna Johannsdottir, Hafdis Th. Helgadottir, Ásgeir Sigurðsson, Valgerður Steinthórsdóttir, Annika Lindblom, Robert S. Sandler, Temitope O. Keku, Karina Banasik, Torben Jørgensen, Daniel R. Witte, Torben F. Hansen, Oluf Borbye Pedersen, Viorel Jinga, David E. Neal, William J. Catàlona, Margaret Wrensch, John K. Wiencke, Robert Brian Jenkins, Eduardo Nagore, Ulla Birgitte Vogel, Lambertus A.L.M. Kiemeney, Rajiv Kumar, Jose Ignacio Mayordomo, Jón Hjaltalín Ólafsson, Augustine Kong, Unnur Arna Thorsteinsdottir, Þórunn Rafnar, Kāri Stefánsson · 发表于：Nature Genetics · 年份：2011 · DOI：10.1038/ng.926 · 被引用次数：305 · 研究领域：Cancer-related Molecular Pathways、Ubiquitin and proteasome pathways、Epigenetics and DNA Methylation