Characterization of a newly derived human sarcoma cell line (HT-1080)

作者：Suraiya Rasheed, Walter A. Nelson‐Rees, Eva M. Toth, Paul M. Arnstein, Murray B. Gardner · 发表于：Cancer · 年份：1974 · DOI：10.1002/1097-0142(197404)33:4<1027::aid-cncr2820330419>3.0.co;2-z · 被引用次数：691 · 研究领域：Virus-based gene therapy research、RNA Interference and Gene Delivery、Telomeres, Telomerase, and Senescence

A tumor cell line was derived from the fibrosarcoma of a 35-year-old Caucasian man who died without having received chemotherapy or radiotherapy. The in vitro growth properties and transplantability into antithymocytic sera treated mice were characteristic of these malignant cells. An aberrant karyology with marker chromosomes was present. No virus particles were detected.