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Tumour suppressor RNF43 is a stem-cell E3 ligase that induces endocytosis of Wnt receptors

作者:Bon‐Kyoung Koo, Maureen Spit, Ingrid Jordens, Teck Yew Low, Daniel E. Stange, Marc van de Wetering, Johan H. van Es, Shabaz Mohammed, Albert J. R. Heck, Madelon M. Maurice, Hans C. Clevers · 发表于:Nature · 年份:2012 · DOI:10.1038/nature11308 · 被引用次数:1030 · 研究领域:Wnt/β-catenin signaling in development and cancer、Cancer Cells and Metastasis、Cancer-related gene regulation