The Histologic Type and Stage Distribution of Ovarian Carcinomas of Surface Epithelial Origin

作者：Jeffrey D. Seidman, Iren Horkayne‐Szakaly, Moutaz Haiba, Charles R. Boice, Robert J. Kurman, Brigitte M. Ronnett · 发表于：International Journal of Gynecological Pathology · 年份：2003 · DOI：10.1097/01.pgp.0000101080.35393.16 · 被引用次数：567 · 研究领域：Ovarian cancer diagnosis and treatment、Intraperitoneal and Appendiceal Malignancies、Endometriosis Research and Treatment

Advances over the past decade suggest a need to reassess the distribution of ovarian surface epithelial tumors. A series of 220 consecutive invasive ovarian carcinomas, including carcinosarcomas and peritoneal carcinomas, was reviewed. Notable findings include: 7% of tumors were carcinosarcomas; 22% of cases of peritoneal serous carcinomatosis were of peritoneal origin; <3% of cases were mucinous carcinomas; and only one malignant Brenner tumor (0.5%) and no pure transitional cell carcinomas were identified. If peritoneal carcinomas, carcinosarcomas, and mixed carcinomas with a serous component are combined with serous carcinomas, this group accounts for 78% of all cases and 87% of advanced stage cases, suggesting a greater uniformity to epithelial ovarian cancer than previously appreciated.