The Dermatology Life Quality Index 1994-2007: a comprehensive review of validation data and clinical results

作者：M.K.A. Basra, R. Fenech, Ruben Gatt, Sam Salek, Andrew Yule Finlay · 发表于：British Journal of Dermatology · 年份：2008 · DOI：10.1111/j.1365-2133.2008.08832.x · 被引用次数：796 · 研究领域：Psoriasis: Treatment and Pathogenesis、Dermatology and Skin Diseases、Skin Protection and Aging

BACKGROUND: The Dermatology Life Quality Index (DLQI) is one of the most widely used dermatology-specific quality of life instruments. Over the last 5 years there has been great interest in its use. OBJECTIVES: To collect and present all information regarding the technical properties and the clinical use of the DLQI from the date it was published to the end of 2007 for use as a single source of reference. METHODS: A detailed literature search was conducted using electronic reference databases and the DLQI library in the Department of Dermatology, Cardiff University. All publications mentioning any aspect of the DLQI, from the time of its development to the end of 2007, were identified and the data concerning the DLQI in terms of its psychometric analysis, and use in clinical trials, epidemiological studies and health services research, were extracted and tabulated with all the relevant references. RESULTS: In total, 272 full articles which have included the DLQI were reviewed. Studies described in these articles were divided into five main categories: psychometric studies, descriptive/epidemiological studies, drug (topical and systemic) trials, clinical practice research, and therapeutic interventions. The DLQI has been used in 33 different skin conditions in 32 countries and is available in 55 languages. Psychometric aspects of the DLQI such as validity, reliability, responsiveness to change, factor structure, and minimal important difference were described in 115 studies. T...