An overview of the Registry of Toxic Effects of Chemical Substances (RTECS): Critical information on chemical hazards

作者：Doris V. Sweet, Vernon P. Anderson, Jiakun Fang · 发表于：ACS Chemical Health & Safety · 年份：1999 · DOI：10.1016/s1074-9098(99)00058-1 · 被引用次数：32 · 研究领域：Chemical Safety and Risk Management、Risk and Safety Analysis、Carcinogens and Genotoxicity Assessment

Since 1971, the National Institute for Occupational Safety and Health (NIOSH) has been building RTECS into a definitive toxicological database with supplemental information pertinent to both the chemical industry and the occupational safety and health community. RTECS provides the technical data needed to assess workers' exposures to chemicals, particularly to lesser-known-and-used chemical substances. OSHA has designated RTECS as a primary source for toxicity data for Material Safety Data Sheets in its Hazard Communications Rule. In recent years, RTECS has grown to include more than 145,000 chemical substances, 337,000 synonymous names, and 287,000 individual toxicity citations. The toxicological data are organized into six fields: primary irritation, mutagenic effects, reproductive effects, tumorigenic effects, acute toxicity, and other multiple dose toxicity. Each data line includes the citation to its bibliographic source. RTECS provides a host of reference data including, but not limited to: CAS Numbers, OSHA PELs, ACGIH TLVs, NIOSH RELs, Carcinogenic assessments, Beilstein Reference Numbers, Bioassay results from the National Toxicology Program, and status lines pointing to several programs of the EPA [Toxic Substance Control Act (TSCA), Genetic Toxicology (GENE-TOX), Toxic Substance Control Act Test Submission (TSCATS), Integrated Risk Information System (IRIS)].