Aspergillus Meningitis in Sri Lanka — A Post-Tsunami Effect?

作者：Padma Sriyani Gunaratne, Chandrika N. Wijeyaratne, Harshalal Rukka Seneviratne · 发表于：New England Journal of Medicine · 年份：2007 · DOI：10.1056/nejmc062547 · 被引用次数：38 · 研究领域：Antifungal resistance and susceptibility、Bacterial Infections and Vaccines、Ocular Infections and Treatments

To the Editor: An outbreak of meningitis from infection with Aspergillus fumigatus after the administration of spinal anesthesia for cesarean section occurred between July 2 and July 25, 2005, in Colombo, Sri Lanka. The patients were five previously healthy women. Their median age was 27 years (range, 21 to 38) (Table 1). They had received spinal anesthesia from different surgical teams in two maternity hospitals. The mean incubation period was 11.2 days. Fever, headache, and nuchal rigidity were common presentations. Remittent fever continued despite initial treatment with broad-spectrum intravenous antibiotics. Papilledema, lateral rectus palsy, and cerebral infarction and hemorrhage developed . . .