A multivariate analysis of clinical and pathological variables in prognosis after resection of large bowel cancer

作者：P. H. Chapuis, O. F. Dent, Richard Fisher, R. C. Newland, Murray T. Pheils, E.J. Smyth, K. Colquhoun · 发表于：British journal of surgery · 年份：1985 · DOI：10.1002/bjs.1800720909 · 被引用次数：467 · 研究领域：Colorectal Cancer Surgical Treatments、Colorectal and Anal Carcinomas、Colorectal Cancer Treatments and Studies

Data on 709 patients who had a resection for colorectal carcinoma at Concord Hospital between 1971 and 1980 were studied to determine the independent effects on survival of several patient characteristics and pathological variables using the Cox regression model. Clinicopathological stage had the strongest association. Other variables ranked according to their relative importance independent of stage were: histological grade, level of direct spread, the presence of venous invasion, age and sex of the patient and the presence of obstruction.