Homogeneous asymmetric transfer hydrogenation of ketones using a ruthenium catalyst anchored on chitosan: natural chirality at work

作者：Mathieu Babin, Roxanne Clément, Jonathan Gagnon, Frédéric‐Georges Fontaine · 发表于：New Journal of Chemistry · 年份：2012 · DOI：10.1039/c2nj40175d · 被引用次数：29 · 研究领域：Asymmetric Hydrogenation and Catalysis、Catalysis for Biomass Conversion、Surface Chemistry and Catalysis

A pivaloyl functionalized chitosan biopolymer was used as a polyligand for the [Ru(p-cymene)Cl2] moiety. The functionalized biopolymer containing a metal to saccharide ratio of 0.33 was used as a catalyst for the asymmetric transfer hydrogenation of ketones. The reactions gave yields up to 80% and enantiomeric excesses up to 72%, with the intrinsic chirality of chitosan being the only source of enantioselection.