Management and survival of female breast cancer: Results of a national survey by the American college of surgeons

作者：Takuma Nemoto, JOSEF VANA, Ramez Naguib Bedwani, Harvey W. Baker, Frank H. McGregor, Gerald P. Murphy · 发表于：Cancer · 年份：1980 · DOI：10.1002/1097-0142(19800615)45:12<2917::aid-cncr2820451203>3.0.co;2-m · 被引用次数：670 · 研究领域：Breast Cancer Treatment Studies、Global Cancer Incidence and Screening、Breast Lesions and Carcinomas

This is a resume of a Breast Cancer Survey carried out by the American College of Surgeons in 1978. Four hundred and ninety-eight hospitals in 47 states, Washington, D.C., and Puerto Rico participated, contributing a total of 24,136 female patients with histologically confirmed breast cancer. In these patients, five-year cure rates were 60.5% for clinically localized disease and 33.9% for regional disease. Five-year survival rates were 72.8% for localized disease and 49.1% for regional disease. From the 1960's into the early 1970's, there was a gradual shift away from radical mastectomy towards so-called modified radical mastectomy. In a group of patients treated by either radical or modified mastectomies, the axillary nodal status, size of the tumor, and location of the tumor were examined in relation to the prognosis. In the study of number of metastatic nodes in the axilla, there were reduced cure and survival rates in patients with one or more positive nodes as compared to those with negative axillary nodes. With the increase in the number of positive nodes, there was a continuing associated decline in survival and cure. The clinical size of the tumor also correlated well to the prognosis. With the increase in the size of the tumor, there was a gradual increase in the probability of axillary nodal involvement. However, in the group of patients with tumor size smaller than 1 cm, axillary metastasis occurred in 25%. When the axillary nodes were involved, the cure rate in th...