Hypertension in Adults Across the Age Spectrum

作者：Donald M. Lloyd‐Jones, Jane Cooper Evans, Daniel Levy · 发表于：JAMA · 年份：2005 · DOI：10.1001/jama.294.4.466 · 被引用次数：632 · 研究领域：Blood Pressure and Hypertension Studies、Dementia and Cognitive Impairment Research、Sodium Intake and Health

CONTEXT: Data are sparse regarding current rates of hypertension treatment and control, and risks associated with hypertension, among persons older than 80 years. OBJECTIVE: To determine the prevalence of blood pressure stages, hypertension treatment and control, and cardiovascular risk among older patients with hypertension. DESIGN, SETTING, AND PARTICIPANTS: A community-based cohort study in which data were collected during all Framingham Heart Study examinations attended in the 1990s. Participants were pooled according to age: younger than 60 years, 60 to 79 years, or 80 years or older. There were 5296 participants who contributed 14 458 person-examinations of observation, including 7135 hypertensive person-examinations (4919 treated). MAIN OUTCOME MEASURES: Prevalence of hypertension, its treatment, and its control were compared across age groups. Risks for incident cardiovascular disease during follow-up of up to 6 years were estimated as multivariate-adjusted hazard ratios (HRs) and 95% confidence intervals (CIs) using Cox proportional hazards regression. RESULTS: Prevalence of hypertension and drug treatment increased with advancing age, whereas control rates were markedly lower in older women (systolic <140 and diastolic <90 mm Hg). For ages younger than 60 years, 60 to 79, and 80 years and older, respectively, control rates were 38%, 36%, and 38% in men (P = .30) and 38%, 28%, and 23% in women (P<.001). Relative risks for cardiovascular disease associated with increa...