MYASTHENIA GRAVIS IN A MOTHER AND HER NEWBORN SON

作者：George E. McKeever · 发表于：JAMA · 年份：1951 · DOI：10.1001/jama.1951.73670210013007f · 被引用次数：18 · 研究领域：Myasthenia Gravis and Thymoma、Pituitary Gland Disorders and Treatments、Salivary Gland Tumors Diagnosis and Treatment

Myasthenia gravis is a disease that lends itself well to study. The history and physical findings are well defined, although variable. Almost absolute proof of the diagnosis is available in the test dose of neostigmine (prostigmin®). As a result, many articles are to be found in the recent literature. Numerous series of cases have been available for the study of such particular manifestations of the disease as the ocular and the bulbar. Certain aspects, however, are sufficiently rare to warrant case reports. Among these are cases of myasthenia gravis complicating pregnancy and congenital myasthenia gravis. Of the latter, a total of 10 cases has been reported, the first in 1942.1aOf the 10 cases, the congenital nature of the disease was determined by retrospect in four. In the other six cases the diagnosis was made in the neonatal period. In this report the seventh known case of myasthenia gravis