Chronic Electrical Stimulation of the Ventralis Intermedius Nucleus of the Thalamus and of Other Nuclei as a Treatment for Parkinsonʼs Disease

作者：Alim Louis Benabid, Abdhelhamid Benazzouz, Dongming Gao, D. Hoffmann, Patricia Dowsey Limousin, Adnan Koudsié, Paul Krack, Pierre Pollak · 发表于：Techniques in Neurosurgery · 年份：1999 · DOI：10.1097/00127927-199905010-00003 · 被引用次数：75 · 研究领域：Neurological disorders and treatments、Neuroscience and Neural Engineering、Photoreceptor and optogenetics research

Abstract:During stereotaxy in nonanesthetized patients with Parkinson's disease or essential tremor, tremor was suppressed by test stimulation of the thalamic ventralis intermedius nucleus (Vim) at high frequency (130 Hz). Based on this finding, the authors have used chronic stimulation of the Vim a