MUCOID STRAINS OF PSEUDOMONAS AERUGINOSA: THE INFLUENCE OF CULTURE MEDIUM ON THE STABILITY OF MUCUS PRODUCTION

作者：John R. W. Govan · 发表于：Journal of Medical Microbiology · 年份：1975 · DOI：10.1099/00222615-8-4-513 · 被引用次数：148 · 研究领域：Plant Pathogenic Bacteria Studies、Legume Nitrogen Fixing Symbiosis、Plant-Microbe Interactions and Immunity

Mucoid strains of Pseudomonas aeruginosa isolated from the respiratory tract of patients with cystic fibrosis (CF), those obtained from non-CF patients, and those obtained in vitro by the action of phage, were found to be stable in their mucoid colonial form when serially subcultured on deoxycholate-citrate agar. The ability of anionic, cationic and neutral surfactants to stabilise mucus production is described. The possible importance of dipalmitoyl lecithin as a stabilising agent for mucus production in vivo is considered, with particular reference to the role of mucoid P. aeruginosa in CF disease.