Improved accuracy of clinical diagnosis of Lewy body Parkinson’s disease

作者：Andrew Hughes, Susan E. Daniel, Andrew J. Lees · 发表于：Neurology · 年份：2001 · DOI：10.1212/wnl.57.8.1497 · 被引用次数：809 · 研究领域：Parkinson's Disease Mechanisms and Treatments、Neurological disorders and treatments、Ginkgo biloba and Cashew Applications

The authors studied the accuracy of clinical diagnosis of idiopathic PD (IPD) in 100 consecutive clinically diagnosed cases that came to neuropathological examination. Ninety fulfilled pathologic criteria for IPD. Ten were misdiagnosed: multiple system atrophy (six), progressive supranuclear palsy (two), post-encephalitic parkinsonism (one), and vascular parkinsonism (one). Assessment of the clinical features suggests that an accuracy of 90% may be the highest that can be expected using current diagnostic criteria.